Pheochromocytoma

Prognosis

If malignant¹

• 5y OS ~60-80%
• PPGL-attributable death 85%
  • Modes of death?
• Poor prognostic factors: sporadic disease, hypersecretion
• Favorable prognostic factors: H&N disease, SDHx mutation (availability of drugs, usu younger, more often H&N locale, less likely to be hypersecretors)

If benign²

• 5y OS >95%