Pheochromocytoma

• Detected incidence for PPGL: 0.6/100k, rising with time
• ~0.5% of all pts with HTN
• ~4% in adrenal incidentaloma
• >35% of cases are associated w germline mutations
• ~2/3-3/4 p/w with hormone-related sx, ~2/3-3/4 p/w with tumor-related sx