Anaplastic Thyroid Carcinoma

Case presentation

73M w CAD (MI x1, no interventions), T2DM (not on insulin), hx smoking (0.3 ppd x 45y, quit 10y ago), p/w 50lb weight loss, dysphagia, ~4mo enlarging neck mass, found to have AKI and large neck mass on imaging.

TImeline

• 2022-04 intermittent sinus issues began, multiple courses of abx, voice hoarse
• 2022-07-12 PCP visit: noted 36lb weight loss since January. Dysphagia at times. Left face hurts when he lies down. Nontender thryomegaly present on exam. TSH 7.14
• 2022-07-13 US thyroid: left lobe heterogenous and 6.8x5.6x4.4 (R lobe 3.4x1.3x1.4)
• 2022-08-14 presented to VUMC